Feeling thermally comfortable is one of the aspects that occupants value most in a building, and yet, mitigating localized thermal comfort is rarely a priority during the design process. In many hospital environments, mechanical systems, like perimeter heating, compensate for shortcomings in envelope performance to provide a thermally comfortable environment for its various occupants. However, with an increased interest in maximizing energy efficiency and façade transparency, as well as providing healthy spaces for occupants, our Building Science Group sought to understand as early as the schematic design phase which façade properties negatively or positively impact comfort. This is especially important in a health care environment where the ideal comfort zone varies from patient rooms to doctor spaces.